CK 8/Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Alternative Names: CK 8/ Cytokeratin 8 / Keratin 8 CK-8, cytokeratin-8, keratin, type II cytoskeletal 8, keratin-8
| Product Name: | Anti-CK8 Antibody |
|---|---|
| Reference #: | RU00006 |
| Clone #: | 1B12 |
| Source #: | Mouse Monoclonal |
| Reactivity: | Human |
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